{"id":14254,"date":"2020-02-24T18:22:57","date_gmt":"2020-02-24T10:22:57","guid":{"rendered":"https:\/\/id-ea.org\/tbe\/?p=14254"},"modified":"2020-02-24T18:23:00","modified_gmt":"2020-02-24T10:23:00","slug":"snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics","status":"publish","type":"post","link":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/","title":{"rendered":"Snapshot week 9\/2020 <br>Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics"},"content":{"rendered":"<span class=\"cb-itemprop\" itemprop=\"reviewBody\">\n<p class=\"wp-block-paragraph\">Albinsson et al.<br>Antibody responses to tick-borne encephalitis virus non-structural protein 1 and whole virus-antigen \u2013 a new tool in the assessment of suspected vaccine failure patients<br><em>Infect. Ecol. Epidemiol<\/em>. 2019, 9:1, 1696132, doi: 10.1080\/20008686.2019.1696132<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">TBE vaccines are highly effective. However, vaccine failures have been\nreported (e.g. see Snapshot week 10\/2020). The detection of antibodies directed\nto TBE virus non-structural protein 1 (NS-1) and\/or to the envelope protein\n(and other structural viral antigens) may help to discriminate, if a patient\nhas developed disease caused by a viral infection (despite vaccination) or if\nthe antibody response is (only) directed to vaccine antigens. NS-1 is not part\nof the commercially available (killed whole virus) vaccines containing only\nstructural antigens, and thus, vaccinees do not develop antibodies to NS-1.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A Swedish group has analyzed 17 serum samples and 18 CSF samples from 14\npatients who had a documented history of TBE vaccination but had clinical and laboratory\nsuspected TBE virus infections. 11 out of 14 patients were found IgM antibody\npositive to NS-1 in serum or CSF, while all patients tested positive for whole\nvirus antigen. The positive test for NS-1 indicate a current or recent TBE\nvirus infection and testing for NS-1 antibodies may help to identify vaccine\nfailures.<\/p>\n<\/span>","protected":false},"excerpt":{"rendered":"<p>Albinsson et al.Antibody responses to tick-borne encephalitis virus non-structural protein 1 and whole virus-antigen \u2013 a new tool in the assessment of suspected vaccine failure patientsInfect. Ecol. Epidemiol. 2019, 9:1, 1696132, doi: 10.1080\/20008686.2019.1696132 TBE vaccines are highly effective. However, vaccine failures have been reported (e.g. see Snapshot week 10\/2020). The detection of antibodies directed to TBE virus non-structural protein 1 (NS-1) and\/or to the envelope protein (and other structural viral antigens) may help to discriminate, if a patient has developed disease caused by a viral infection (despite vaccination) or if the antibody response is (only) directed to vaccine antigens. NS-1 is not part of the commercially available (killed whole virus) vaccines containing only structural antigens, and thus, vaccinees do not develop antibodies to NS-1. A Swedish group has analyzed 17 serum samples and 18 CSF samples from 14 patients who had a documented history of TBE vaccination but had clinical and laboratory suspected TBE virus infections. 11 out of 14 patients were found IgM antibody positive to NS-1 in serum or CSF, while all patients tested positive for whole virus antigen. The positive test for NS-1 indicate a current or recent TBE virus infection and testing for NS-1 antibodies may help to identify vaccine failures.<\/p>\n","protected":false},"author":6,"featured_media":12864,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[18],"tags":[436,437,438,208],"coauthors":[81],"class_list":["post-14254","post","type-post","status-publish","format-standard","has-post-thumbnail","category-snapshot","tag-diagnostics","tag-non-structural-protein-1-ns-1","tag-structural-proteins","tag-vaccine-failure"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Snapshot week 9\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics - TBE Book<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Snapshot week 9\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics - TBE Book\" \/>\n<meta property=\"og:description\" content=\"Albinsson et al.Antibody responses to tick-borne encephalitis virus non-structural protein 1 and whole virus-antigen \u2013 a new tool in the assessment of suspected vaccine failure patientsInfect. Ecol. Epidemiol. 2019, 9:1, 1696132, doi: 10.1080\/20008686.2019.1696132 TBE vaccines are highly effective. However, vaccine failures have been reported (e.g. see Snapshot week 10\/2020). The detection of antibodies directed to TBE virus non-structural protein 1 (NS-1) and\/or to the envelope protein (and other structural viral antigens) may help to discriminate, if a patient has developed disease caused by a viral infection (despite vaccination) or if the antibody response is (only) directed to vaccine antigens. NS-1 is not part of the commercially available (killed whole virus) vaccines containing only structural antigens, and thus, vaccinees do not develop antibodies to NS-1. A Swedish group has analyzed 17 serum samples and 18 CSF samples from 14 patients who had a documented history of TBE vaccination but had clinical and laboratory suspected TBE virus infections. 11 out of 14 patients were found IgM antibody positive to NS-1 in serum or CSF, while all patients tested positive for whole virus antigen. The positive test for NS-1 indicate a current or recent TBE virus infection and testing for NS-1 antibodies may help to identify vaccine failures.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/\" \/>\n<meta property=\"og:site_name\" content=\"TBE Book\" \/>\n<meta property=\"article:published_time\" content=\"2020-02-24T10:22:57+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-02-24T10:23:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1180\" \/>\n\t<meta property=\"og:image:height\" content=\"250\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Michael Br\u00f6ker\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Michael Br\u00f6ker\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/\"},\"author\":{\"name\":\"augustine\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#\\\/schema\\\/person\\\/2f903afeb7534df7457d2e3f6d30f64c\"},\"headline\":\"Snapshot week 9\\\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics\",\"datePublished\":\"2020-02-24T10:22:57+00:00\",\"dateModified\":\"2020-02-24T10:23:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/\"},\"wordCount\":207,\"publisher\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/TBE-Snapshots.jpg\",\"keywords\":[\"diagnostics\",\"non-structural protein 1 (NS-1)\",\"structural proteins\",\"vaccine failure\"],\"articleSection\":[\"Snapshot\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/\",\"name\":\"Snapshot week 9\\\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics - TBE Book\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/TBE-Snapshots.jpg\",\"datePublished\":\"2020-02-24T10:22:57+00:00\",\"dateModified\":\"2020-02-24T10:23:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/#primaryimage\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/TBE-Snapshots.jpg\",\"contentUrl\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/TBE-Snapshots.jpg\",\"width\":1180,\"height\":250},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Snapshot week 9\\\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#website\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/\",\"name\":\"The TBE Book\",\"description\":\"Tick-borne Encephalitis (TBE)\",\"publisher\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#organization\",\"name\":\"Global Health Press\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2019\\\/01\\\/logo-PNG.png\",\"contentUrl\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2019\\\/01\\\/logo-PNG.png\",\"width\":1000,\"height\":715,\"caption\":\"Global Health Press\"},\"image\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#\\\/schema\\\/person\\\/2f903afeb7534df7457d2e3f6d30f64c\",\"name\":\"augustine\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/81a51e276681ab241e1fba1ee7f85ca6fcd68b139ab41edba2d0442a923df1f6?s=96&d=mm&r=ge035e25b3672069f7222fdb9b71e7000\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/81a51e276681ab241e1fba1ee7f85ca6fcd68b139ab41edba2d0442a923df1f6?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/81a51e276681ab241e1fba1ee7f85ca6fcd68b139ab41edba2d0442a923df1f6?s=96&d=mm&r=g\",\"caption\":\"augustine\"},\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/author\\\/augustine-augustine\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Snapshot week 9\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics - TBE Book","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/","og_locale":"en_US","og_type":"article","og_title":"Snapshot week 9\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics - TBE Book","og_description":"Albinsson et al.Antibody responses to tick-borne encephalitis virus non-structural protein 1 and whole virus-antigen \u2013 a new tool in the assessment of suspected vaccine failure patientsInfect. Ecol. Epidemiol. 2019, 9:1, 1696132, doi: 10.1080\/20008686.2019.1696132 TBE vaccines are highly effective. However, vaccine failures have been reported (e.g. see Snapshot week 10\/2020). The detection of antibodies directed to TBE virus non-structural protein 1 (NS-1) and\/or to the envelope protein (and other structural viral antigens) may help to discriminate, if a patient has developed disease caused by a viral infection (despite vaccination) or if the antibody response is (only) directed to vaccine antigens. NS-1 is not part of the commercially available (killed whole virus) vaccines containing only structural antigens, and thus, vaccinees do not develop antibodies to NS-1. A Swedish group has analyzed 17 serum samples and 18 CSF samples from 14 patients who had a documented history of TBE vaccination but had clinical and laboratory suspected TBE virus infections. 11 out of 14 patients were found IgM antibody positive to NS-1 in serum or CSF, while all patients tested positive for whole virus antigen. The positive test for NS-1 indicate a current or recent TBE virus infection and testing for NS-1 antibodies may help to identify vaccine failures.","og_url":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/","og_site_name":"TBE Book","article_published_time":"2020-02-24T10:22:57+00:00","article_modified_time":"2020-02-24T10:23:00+00:00","og_image":[{"width":1180,"height":250,"url":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg","type":"image\/jpeg"}],"author":"Michael Br\u00f6ker","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Michael Br\u00f6ker","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/#article","isPartOf":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/"},"author":{"name":"augustine","@id":"https:\/\/tbenews.com\/tbe\/#\/schema\/person\/2f903afeb7534df7457d2e3f6d30f64c"},"headline":"Snapshot week 9\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics","datePublished":"2020-02-24T10:22:57+00:00","dateModified":"2020-02-24T10:23:00+00:00","mainEntityOfPage":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/"},"wordCount":207,"publisher":{"@id":"https:\/\/tbenews.com\/tbe\/#organization"},"image":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/#primaryimage"},"thumbnailUrl":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg","keywords":["diagnostics","non-structural protein 1 (NS-1)","structural proteins","vaccine failure"],"articleSection":["Snapshot"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/","url":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/","name":"Snapshot week 9\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics - TBE Book","isPartOf":{"@id":"https:\/\/tbenews.com\/tbe\/#website"},"primaryImageOfPage":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/#primaryimage"},"image":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/#primaryimage"},"thumbnailUrl":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg","datePublished":"2020-02-24T10:22:57+00:00","dateModified":"2020-02-24T10:23:00+00:00","breadcrumb":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/#primaryimage","url":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg","contentUrl":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg","width":1180,"height":250},{"@type":"BreadcrumbList","@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-9-2020-antibodies-to-ns-1-a-useful-tool-for-tbe-diagnostics\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/tbenews.com\/tbe\/"},{"@type":"ListItem","position":2,"name":"Snapshot week 9\/2020 Antibodies to NS-1 \u2013 a useful tool for TBE diagnostics"}]},{"@type":"WebSite","@id":"https:\/\/tbenews.com\/tbe\/#website","url":"https:\/\/tbenews.com\/tbe\/","name":"The TBE Book","description":"Tick-borne Encephalitis (TBE)","publisher":{"@id":"https:\/\/tbenews.com\/tbe\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/tbenews.com\/tbe\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/tbenews.com\/tbe\/#organization","name":"Global Health Press","url":"https:\/\/tbenews.com\/tbe\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/tbenews.com\/tbe\/#\/schema\/logo\/image\/","url":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2019\/01\/logo-PNG.png","contentUrl":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2019\/01\/logo-PNG.png","width":1000,"height":715,"caption":"Global Health Press"},"image":{"@id":"https:\/\/tbenews.com\/tbe\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/tbenews.com\/tbe\/#\/schema\/person\/2f903afeb7534df7457d2e3f6d30f64c","name":"augustine","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/81a51e276681ab241e1fba1ee7f85ca6fcd68b139ab41edba2d0442a923df1f6?s=96&d=mm&r=ge035e25b3672069f7222fdb9b71e7000","url":"https:\/\/secure.gravatar.com\/avatar\/81a51e276681ab241e1fba1ee7f85ca6fcd68b139ab41edba2d0442a923df1f6?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/81a51e276681ab241e1fba1ee7f85ca6fcd68b139ab41edba2d0442a923df1f6?s=96&d=mm&r=g","caption":"augustine"},"url":"https:\/\/tbenews.com\/tbe\/author\/augustine-augustine\/"}]}},"_links":{"self":[{"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/posts\/14254","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/comments?post=14254"}],"version-history":[{"count":1,"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/posts\/14254\/revisions"}],"predecessor-version":[{"id":14255,"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/posts\/14254\/revisions\/14255"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/media\/12864"}],"wp:attachment":[{"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/media?parent=14254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/categories?post=14254"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/tags?post=14254"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/tbenews.com\/tbe\/wp-json\/wp\/v2\/coauthors?post=14254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}