{"id":18383,"date":"2021-07-12T11:13:47","date_gmt":"2021-07-12T03:13:47","guid":{"rendered":"https:\/\/tbenews.com\/tbe\/?p=18383"},"modified":"2021-07-12T11:15:50","modified_gmt":"2021-07-12T03:15:50","slug":"snapshot-week-28-2021tbe-in-a-very-young-boy","status":"publish","type":"post","link":"https:\/\/tbenews.com\/tbe\/snapshot-week-28-2021tbe-in-a-very-young-boy\/","title":{"rendered":"Snapshot week 28\/2021
TBE in a very young boy"},"content":{"rendered":"\n

Krbkova et al.
Tick-borne encephalitis in an 8.5-month-old boy suspected of febrile seizures.
Microorganisms.<\/em> 2021; 9:1425. doi, 10.3390\/microorganisms9071425<\/p>\n\n\n\n

In young children, TBE is mostly mild and rare. Hence, most countries in which TBE is endemic do not recommend vaccinating very young children and infants. Generally, TBE vaccination starts at the age of three years (e.g., Germany) or not before six years (e.g., Switzerland), and only in highly endemic areas, vaccination below the age of three years is not uncommon (e.g., southeastern regions of Austria).<\/p>\n\n\n\n

A Czech team has now published a case report about an 8.5-month-old boy \u2013 healthy and fully vaccinated according to the vaccination recommendations \u2013 who became ill one week after a tick bite. Symptoms started with an exanthema subitum and then, rectal temperature of 40\u00b0C was measured. Symmetric seizures pronounced in the lower extremities and unconsciousness were observed. After admission to the hospital, comprehensive clinical examinations and laboratory analyses were carried out. Lyme neuroborreliosis was suspected and treatment with ceftriaxone was started and dexamethasone was applied for five days. Antibiotic treatment was discontinued after Lyme borreliosis was excluded and TBE specific IgM and IgG ELISA antibodies were detected in the CSF. TBE virus infection was verified by neutralization assay.<\/p>\n\n\n\n

The boy was discharged home with no detectable sequelae and neurological follow-up showed no abnormalities. NT antibody titers increased at his first control at one month and after half a year.<\/p>\n\n\n\n

The authors conclude that this case provides information for discussions about early vaccination of individuals (already in infancy) living in highly endemic areas.<\/p>\n<\/span>","protected":false},"excerpt":{"rendered":"

Krbkova et al.Tick-borne encephalitis in an 8.5-month-old boy suspected of febrile seizures.Microorganisms. 2021; 9:1425. doi, 10.3390\/microorganisms9071425 In young children, TBE is mostly mild and rare. Hence, most countries in which TBE is endemic do not recommend vaccinating very young children and infants. Generally, TBE vaccination starts at the age of three years (e.g., Germany) or not before six years (e.g., Switzerland), and only in highly endemic areas, vaccination below the age of three years is not uncommon (e.g., southeastern regions of Austria). A Czech team has now published a case report about an 8.5-month-old boy \u2013 healthy and fully vaccinated according to the vaccination recommendations \u2013 who became ill one week after a tick bite. Symptoms started with an exanthema subitum and then, rectal temperature of 40\u00b0C was measured. Symmetric seizures pronounced in the lower extremities and unconsciousness were observed. After admission to the hospital, comprehensive clinical examinations and laboratory analyses were carried out. Lyme neuroborreliosis was suspected and treatment with ceftriaxone was started and dexamethasone was applied for five days. Antibiotic treatment was discontinued after Lyme borreliosis was excluded and TBE specific IgM and IgG ELISA antibodies were detected in the CSF. TBE virus infection was verified by neutralization assay. The boy was discharged home with no detectable sequelae and neurological follow-up showed no abnormalities. NT antibody titers increased at his first control at one month and after half a year. The authors conclude that this case provides information for discussions about early vaccination of individuals (already in infancy) living in highly endemic areas.<\/p>\n","protected":false},"author":1409,"featured_media":12864,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[18],"tags":[756,755,754],"coauthors":[81,652],"class_list":["post-18383","post","type-post","status-publish","format-standard","has-post-thumbnail","category-snapshot","tag-czech-republic","tag-infant","tag-pediatric-infection"],"yoast_head":"\nSnapshot week 28\/2021TBE in a very young boy - TBE Book<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tbenews.com\/tbe\/snapshot-week-28-2021tbe-in-a-very-young-boy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Snapshot week 28\/2021TBE in a very young boy - TBE Book\" \/>\n<meta property=\"og:description\" content=\"Krbkova et al.Tick-borne encephalitis in an 8.5-month-old boy suspected of febrile seizures.Microorganisms. 2021; 9:1425. doi, 10.3390\/microorganisms9071425 In young children, TBE is mostly mild and rare. Hence, most countries in which TBE is endemic do not recommend vaccinating very young children and infants. Generally, TBE vaccination starts at the age of three years (e.g., Germany) or not before six years (e.g., Switzerland), and only in highly endemic areas, vaccination below the age of three years is not uncommon (e.g., southeastern regions of Austria). A Czech team has now published a case report about an 8.5-month-old boy \u2013 healthy and fully vaccinated according to the vaccination recommendations \u2013 who became ill one week after a tick bite. Symptoms started with an exanthema subitum and then, rectal temperature of 40\u00b0C was measured. Symmetric seizures pronounced in the lower extremities and unconsciousness were observed. After admission to the hospital, comprehensive clinical examinations and laboratory analyses were carried out. Lyme neuroborreliosis was suspected and treatment with ceftriaxone was started and dexamethasone was applied for five days. Antibiotic treatment was discontinued after Lyme borreliosis was excluded and TBE specific IgM and IgG ELISA antibodies were detected in the CSF. TBE virus infection was verified by neutralization assay. The boy was discharged home with no detectable sequelae and neurological follow-up showed no abnormalities. NT antibody titers increased at his first control at one month and after half a year. The authors conclude that this case provides information for discussions about early vaccination of individuals (already in infancy) living in highly endemic areas.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/tbenews.com\/tbe\/snapshot-week-28-2021tbe-in-a-very-young-boy\/\" \/>\n<meta property=\"og:site_name\" content=\"TBE Book\" \/>\n<meta property=\"article:published_time\" content=\"2021-07-12T03:13:47+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-07-12T03:15:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1180\" \/>\n\t<meta property=\"og:image:height\" content=\"250\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Michael Br\u00f6ker, IT\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Michael Br\u00f6ker, IT\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-28-2021tbe-in-a-very-young-boy\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-28-2021tbe-in-a-very-young-boy\\\/\"},\"author\":{\"name\":\"IT\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#\\\/schema\\\/person\\\/6dd4b733e0a9724f047e3b700d0995f6\"},\"headline\":\"Snapshot week 28\\\/2021 TBE in a very young boy\",\"datePublished\":\"2021-07-12T03:13:47+00:00\",\"dateModified\":\"2021-07-12T03:15:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-28-2021tbe-in-a-very-young-boy\\\/\"},\"wordCount\":264,\"publisher\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-28-2021tbe-in-a-very-young-boy\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/TBE-Snapshots.jpg\",\"keywords\":[\"Czech Republic\",\"infant\",\"pediatric infection\"],\"articleSection\":[\"Snapshot\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-28-2021tbe-in-a-very-young-boy\\\/\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-28-2021tbe-in-a-very-young-boy\\\/\",\"name\":\"Snapshot week 28\\\/2021 TBE in a very young boy - 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