{"id":18533,"date":"2021-11-08T11:29:04","date_gmt":"2021-11-08T03:29:04","guid":{"rendered":"https:\/\/tbenews.com\/tbe\/?p=18533"},"modified":"2021-11-11T16:06:45","modified_gmt":"2021-11-11T08:06:45","slug":"snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans","status":"publish","type":"post","link":"https:\/\/tbenews.com\/tbe\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\/","title":{"rendered":"Snapshot week 45\/2021<br>Rapid transmission of Powassan virus from ticks to humans"},"content":{"rendered":"<span class=\"cb-itemprop\" itemprop=\"reviewBody\">\n<p class=\"wp-block-paragraph\">Feder et al.<br>Powassan virus encephalitis following brief attachment of Connecticut deer ticks.<br><em>Clin Infect Dis.<\/em> 2021;73(7): e2350-4. doi:10.1093\/cid\/ciaa1183<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Powassan virus (POW virus) is a flavivirus belonging to the tick-borne encephalitis complex and has been reported from North America (New England States and Midwestern USA) and Eastern Russia (see also <a href=\"https:\/\/tbenews.com\/tbe\/snapshot-week-25-2021-a-vaccine-candidate-to-protect-against-powassan-virus-infection\/\" data-type=\"URL\" data-id=\"https:\/\/tbenews.com\/tbe\/snapshot-week-25-2021-a-vaccine-candidate-to-protect-against-powassan-virus-infection\/\">Snapshot week 25\/2021<\/a>). POW virus can cause severe encephalitis with a case-fatality rate of about 10%, and long-term sequelae are common in survivors (approx. 50%).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Recently, two POW virus encephalitis cases have been reported in infants indicating that the virus can be quickly transmitted following a tick bite.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Case 1<br>Two weeks before a 5-month-old male was hospitalized, a deer tick had been found on the body of the infant and the infant\u2019s father had been outside hunting in the Connecticut woods, and while outside, he had brushed multiple ticks off clothing. The infant\u2019s mother was convinced that the tick was attached for no more than three hours. POW virus infection was diagnosed by IgM ELISA testing and by a specific neutralization test. The infant was severely ill, but by the age of 15 months, the patient\u2019s growth and development became normal.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Case 2<br>13 days before hospitalization, a tick had been removed from the body of a 2-month-old male child. The tick was found not more than six hours after the child\u2019s bath. The family thought most likely that either the father or the dog had brought the tick into the house following a walk. As in case 1, this infant was severely ill and infection by POW virus was verified by positive IgM ELISA and neutralization test. In the tick removed from the infant, POW virus could be detected by RT-PCR.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">POW virus \u2013 like TBE virus \u2013 invades tick salivary glands very rapidly after infection and persists there in unfed ticks for at least 120 days. Both reported cases appear to have been rapidly infected by the bite of infected deer ticks. The authors suggest that parents should be educated about the need to treat outdoor clothing with permethrin, about the possibility that dogs could bring ticks into homes, and that these animals should be inspected after every outdoor exposure.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In this context, one may also take notice of:<br>Hassett EM, Thangamani S. Ecology of Powassan Virus in the United States. <em>Microorganisms<\/em>. 2021;9(11):2317. <a href=\"https:\/\/doi.org\/10.3390\/\"><a href=\"https:\/\/doi.org\/10.3390\/microorganisms9112317\">https:\/\/doi.org\/10.3390\/microorganisms9112317<\/a><\/a><\/p>\n<\/span>","protected":false},"excerpt":{"rendered":"<p>Feder et al.Powassan virus encephalitis following brief attachment of Connecticut deer ticks.Clin Infect Dis. 2021;73(7): e2350-4. doi:10.1093\/cid\/ciaa1183 Powassan virus (POW virus) is a flavivirus belonging to the tick-borne encephalitis complex and has been reported from North America (New England States and Midwestern USA) and Eastern Russia (see also Snapshot week 25\/2021). POW virus can cause severe encephalitis with a case-fatality rate of about 10%, and long-term sequelae are common in survivors (approx. 50%). Recently, two POW virus encephalitis cases have been reported in infants indicating that the virus can be quickly transmitted following a tick bite. Case 1Two weeks before a 5-month-old male was hospitalized, a deer tick had been found on the body of the infant and the infant\u2019s father had been outside hunting in the Connecticut woods, and while outside, he had brushed multiple ticks off clothing. The infant\u2019s mother was convinced that the tick was attached for no more than three hours. POW virus infection was diagnosed by IgM ELISA testing and by a specific neutralization test. The infant was severely ill, but by the age of 15 months, the patient\u2019s growth and development became normal. Case 213 days before hospitalization, a tick had been removed from the body of a 2-month-old male child. The tick was found not more than six hours after the child\u2019s bath. The family thought most likely that either the father or the dog had brought the tick into the house following a walk. As in case 1, this infant was severely ill and infection by POW virus was verified by positive IgM ELISA and neutralization test. In the tick removed from the infant, POW virus could be detected by RT-PCR. POW virus \u2013 like TBE virus \u2013 invades tick salivary glands very rapidly after infection and persists there in unfed ticks for at least 120 days. Both reported cases appear to have been rapidly infected by the bite of infected deer ticks. The authors suggest that parents should be educated about the need to treat outdoor clothing with permethrin, about the possibility that dogs could bring ticks into homes, and that these animals should be inspected after every outdoor exposure. In this context, one may also take notice of:Hassett EM, Thangamani S. Ecology of Powassan Virus in the United States. Microorganisms. 2021;9(11):2317. https:\/\/doi.org\/10.3390\/microorganisms9112317<\/p>\n","protected":false},"author":1354,"featured_media":12864,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[18],"tags":[791,792,793,755,790,747],"coauthors":[81],"class_list":["post-18533","post","type-post","status-publish","format-standard","has-post-thumbnail","category-snapshot","tag-connecticut","tag-deer-tick","tag-encephalitis","tag-infant","tag-north-america","tag-powassan-virus"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Snapshot week 45\/2021Rapid transmission of Powassan virus from ticks to humans - TBE Book<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tbenews.com\/tbe\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Snapshot week 45\/2021Rapid transmission of Powassan virus from ticks to humans - TBE Book\" \/>\n<meta property=\"og:description\" content=\"Feder et al.Powassan virus encephalitis following brief attachment of Connecticut deer ticks.Clin Infect Dis. 2021;73(7): e2350-4. doi:10.1093\/cid\/ciaa1183 Powassan virus (POW virus) is a flavivirus belonging to the tick-borne encephalitis complex and has been reported from North America (New England States and Midwestern USA) and Eastern Russia (see also Snapshot week 25\/2021). POW virus can cause severe encephalitis with a case-fatality rate of about 10%, and long-term sequelae are common in survivors (approx. 50%). Recently, two POW virus encephalitis cases have been reported in infants indicating that the virus can be quickly transmitted following a tick bite. Case 1Two weeks before a 5-month-old male was hospitalized, a deer tick had been found on the body of the infant and the infant\u2019s father had been outside hunting in the Connecticut woods, and while outside, he had brushed multiple ticks off clothing. The infant\u2019s mother was convinced that the tick was attached for no more than three hours. POW virus infection was diagnosed by IgM ELISA testing and by a specific neutralization test. The infant was severely ill, but by the age of 15 months, the patient\u2019s growth and development became normal. Case 213 days before hospitalization, a tick had been removed from the body of a 2-month-old male child. The tick was found not more than six hours after the child\u2019s bath. The family thought most likely that either the father or the dog had brought the tick into the house following a walk. As in case 1, this infant was severely ill and infection by POW virus was verified by positive IgM ELISA and neutralization test. In the tick removed from the infant, POW virus could be detected by RT-PCR. POW virus \u2013 like TBE virus \u2013 invades tick salivary glands very rapidly after infection and persists there in unfed ticks for at least 120 days. Both reported cases appear to have been rapidly infected by the bite of infected deer ticks. The authors suggest that parents should be educated about the need to treat outdoor clothing with permethrin, about the possibility that dogs could bring ticks into homes, and that these animals should be inspected after every outdoor exposure. In this context, one may also take notice of:Hassett EM, Thangamani S. Ecology of Powassan Virus in the United States. Microorganisms. 2021;9(11):2317. https:\/\/doi.org\/10.3390\/microorganisms9112317\" \/>\n<meta property=\"og:url\" content=\"https:\/\/tbenews.com\/tbe\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\/\" \/>\n<meta property=\"og:site_name\" content=\"TBE Book\" \/>\n<meta property=\"article:published_time\" content=\"2021-11-08T03:29:04+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-11-11T08:06:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1180\" \/>\n\t<meta property=\"og:image:height\" content=\"250\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Michael Br\u00f6ker\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Michael Br\u00f6ker\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\\\/\"},\"author\":{\"name\":\"Shaqeez\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#\\\/schema\\\/person\\\/2bc2ab1f56f93257537a0ce8de903224\"},\"headline\":\"Snapshot week 45\\\/2021 Rapid transmission of Powassan virus from ticks to humans\",\"datePublished\":\"2021-11-08T03:29:04+00:00\",\"dateModified\":\"2021-11-11T08:06:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\\\/\"},\"wordCount\":395,\"publisher\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/TBE-Snapshots.jpg\",\"keywords\":[\"Connecticut\",\"deer tick\",\"encephalitis\",\"infant\",\"North America\",\"Powassan virus\"],\"articleSection\":[\"Snapshot\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\\\/\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\\\/\",\"name\":\"Snapshot week 45\\\/2021 Rapid transmission of Powassan virus from ticks to humans - 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TBE Book","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/tbenews.com\/tbe\/snapshot-week-45-2021rapid-transmission-of-powassan-virus-from-ticks-to-humans\/","og_locale":"en_US","og_type":"article","og_title":"Snapshot week 45\/2021Rapid transmission of Powassan virus from ticks to humans - TBE Book","og_description":"Feder et al.Powassan virus encephalitis following brief attachment of Connecticut deer ticks.Clin Infect Dis. 2021;73(7): e2350-4. doi:10.1093\/cid\/ciaa1183 Powassan virus (POW virus) is a flavivirus belonging to the tick-borne encephalitis complex and has been reported from North America (New England States and Midwestern USA) and Eastern Russia (see also Snapshot week 25\/2021). POW virus can cause severe encephalitis with a case-fatality rate of about 10%, and long-term sequelae are common in survivors (approx. 50%). Recently, two POW virus encephalitis cases have been reported in infants indicating that the virus can be quickly transmitted following a tick bite. Case 1Two weeks before a 5-month-old male was hospitalized, a deer tick had been found on the body of the infant and the infant\u2019s father had been outside hunting in the Connecticut woods, and while outside, he had brushed multiple ticks off clothing. The infant\u2019s mother was convinced that the tick was attached for no more than three hours. POW virus infection was diagnosed by IgM ELISA testing and by a specific neutralization test. The infant was severely ill, but by the age of 15 months, the patient\u2019s growth and development became normal. Case 213 days before hospitalization, a tick had been removed from the body of a 2-month-old male child. The tick was found not more than six hours after the child\u2019s bath. The family thought most likely that either the father or the dog had brought the tick into the house following a walk. As in case 1, this infant was severely ill and infection by POW virus was verified by positive IgM ELISA and neutralization test. In the tick removed from the infant, POW virus could be detected by RT-PCR. POW virus \u2013 like TBE virus \u2013 invades tick salivary glands very rapidly after infection and persists there in unfed ticks for at least 120 days. Both reported cases appear to have been rapidly infected by the bite of infected deer ticks. The authors suggest that parents should be educated about the need to treat outdoor clothing with permethrin, about the possibility that dogs could bring ticks into homes, and that these animals should be inspected after every outdoor exposure. In this context, one may also take notice of:Hassett EM, Thangamani S. 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