{"id":18669,"date":"2022-01-24T13:40:06","date_gmt":"2022-01-24T05:40:06","guid":{"rendered":"https:\/\/tbenews.com\/tbe\/?p=18669"},"modified":"2022-01-28T10:31:23","modified_gmt":"2022-01-28T02:31:23","slug":"snapshot-week-4-2022clinical-analysis-of-tbe-and-other-viral-infections","status":"publish","type":"post","link":"https:\/\/tbenews.com\/tbe\/snapshot-week-4-2022clinical-analysis-of-tbe-and-other-viral-infections\/","title":{"rendered":"Snapshot week 4\/2022
Clinical analysis of TBE and other viral infections"},"content":{"rendered":"\n

Ungureanu et al.
Meningitis, meningoencephalitis and encephalitis in Bern: an observational study of 258 patients
BMC Neurol<\/em>. 2021; 21:474. doi:10.1186\/s12883-021-02502-3<\/p>\n\n\n\n

A monocentric, observational study has been conducted to assess the frequency, clinical presentation and long-term outcome (with a focus on sleep disorders and wakefulness) of encephalitis, meningoencephalitis, and meningitis treated in the Inselspital University Hospital Bern, Switzerland.<\/p>\n\n\n\n

From a total of 463 screened patient medical records, 258 patients during a 34-month period were included in the retrospective analysis of the study.<\/p>\n\n\n\n

Of these patients, 46 (18%) were treated for encephalitis, 109 (42%) for nonbacterial meningoencephalitis, 70 (27%) for nonbacterial meningitis and 33 (13%) for bacterial meningoencephalitis\/meningitis. Overall, the most frequent causes were of infectious origin (57%); in 5%, an immune-mediated cause was found; and 36% remained without a known cause.<\/p>\n\n\n\n

TBE virus infection was the most frequently detected cause of meningoencephalitis or meningitis (65\/258 cases, 25%). Fifty-eight patients (89%) presented with meningoencephalitis (including nine cases of meningoencephalomyelitis and meningoencephalomyeloradiculitis), six patients (9%) had meningitis and one patient (2%) had encephalitis.<\/p>\n\n\n\n

The medium time from the onset of signs and symptoms until hospital admission was 5.5 days in encephalitis, 4 days for nonbacterial meningitis and 2 days in bacterial meningoencephalitis\/meningitis.<\/p>\n\n\n\n

A telephone follow-up interview took place at a median of 16 months after hospital discharge. Only 50% of patients with encephalitis and 81% of nonbacterial meningoencephalitis were able to restart work or studies to the same extent as before the acute illness. Persisting neurological manifestations were reported by 56% of patients. Excessive daytime sleepiness and\/or fatigue were frequently reported in the follow-up, and 42% reported sleep-wake disorders, cognitive impairment and memory deficits, headache and epileptic seizures.<\/p>\n<\/span>","protected":false},"excerpt":{"rendered":"

Ungureanu et al.Meningitis, meningoencephalitis and encephalitis in Bern: an observational study of 258 patientsBMC Neurol. 2021; 21:474. doi:10.1186\/s12883-021-02502-3 A monocentric, observational study has been conducted to assess the frequency, clinical presentation and long-term outcome (with a focus on sleep disorders and wakefulness) of encephalitis, meningoencephalitis, and meningitis treated in the Inselspital University Hospital Bern, Switzerland. From a total of 463 screened patient medical records, 258 patients during a 34-month period were included in the retrospective analysis of the study. Of these patients, 46 (18%) were treated for encephalitis, 109 (42%) for nonbacterial meningoencephalitis, 70 (27%) for nonbacterial meningitis and 33 (13%) for bacterial meningoencephalitis\/meningitis. Overall, the most frequent causes were of infectious origin (57%); in 5%, an immune-mediated cause was found; and 36% remained without a known cause. TBE virus infection was the most frequently detected cause of meningoencephalitis or meningitis (65\/258 cases, 25%). Fifty-eight patients (89%) presented with meningoencephalitis (including nine cases of meningoencephalomyelitis and meningoencephalomyeloradiculitis), six patients (9%) had meningitis and one patient (2%) had encephalitis. The medium time from the onset of signs and symptoms until hospital admission was 5.5 days in encephalitis, 4 days for nonbacterial meningitis and 2 days in bacterial meningoencephalitis\/meningitis. A telephone follow-up interview took place at a median of 16 months after hospital discharge. Only 50% of patients with encephalitis and 81% of nonbacterial meningoencephalitis were able to restart work or studies to the same extent as before the acute illness. Persisting neurological manifestations were reported by 56% of patients. Excessive daytime sleepiness and\/or fatigue were frequently reported in the follow-up, and 42% reported sleep-wake disorders, cognitive impairment and memory deficits, headache and epileptic seizures.<\/p>\n","protected":false},"author":1354,"featured_media":12864,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[18],"tags":[602,793,852,851,853,228],"coauthors":[81],"class_list":["post-18669","post","type-post","status-publish","format-standard","has-post-thumbnail","category-snapshot","tag-clinical-study","tag-encephalitis","tag-meningitis","tag-meningoencephalitis","tag-sleep-wake-disorders","tag-switzerland"],"yoast_head":"\nSnapshot week 4\/2022Clinical analysis of TBE and other viral infections - TBE Book<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tbenews.com\/tbe\/snapshot-week-4-2022clinical-analysis-of-tbe-and-other-viral-infections\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Snapshot week 4\/2022Clinical analysis of TBE and other viral infections - TBE Book\" \/>\n<meta property=\"og:description\" content=\"Ungureanu et al.Meningitis, meningoencephalitis and encephalitis in Bern: an observational study of 258 patientsBMC Neurol. 2021; 21:474. doi:10.1186\/s12883-021-02502-3 A monocentric, observational study has been conducted to assess the frequency, clinical presentation and long-term outcome (with a focus on sleep disorders and wakefulness) of encephalitis, meningoencephalitis, and meningitis treated in the Inselspital University Hospital Bern, Switzerland. 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