{"id":18808,"date":"2022-03-21T14:03:39","date_gmt":"2022-03-21T06:03:39","guid":{"rendered":"https:\/\/tbenews.com\/tbe\/?p=18808"},"modified":"2022-03-22T15:39:55","modified_gmt":"2022-03-22T07:39:55","slug":"snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers","status":"publish","type":"post","link":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/","title":{"rendered":"Snapshot week 12\/2022<br>Short-term protection of TBE vaccination for travelers"},"content":{"rendered":"<span class=\"cb-itemprop\" itemprop=\"reviewBody\">\n<p class=\"wp-block-paragraph\">Pugh et al.<br>Effectiveness of two doses of tick-borne encephalitis (TBE) vaccine<br><em>J. Travel Med.<\/em> 2022; in press. doi:10.1093\/jtm\/taab193<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Since autumn 2021, a TBE vaccine (based on the European subtype, strain Neud\u00f6rfl) has been licensed in the USA. The primary vaccination series consists of three injections for individuals aged \u22651 year. The doses are administered at day 0, 14 days to 3 months later (1\u20133 months for individuals aged 1\u201315 years) and 5\u201312 months after the second dose.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Travelers mostly ask for health advice shortly before they travel, and thus there would not be sufficient time to complete the primary vaccination series prior to travelling to TBE endemic areas.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Would two doses of TBE vaccine help to protect against TBE in the short term? This has been answered by a recently published analysis of TBE vaccination in Austria for the years 2018\u20132020.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The authors analyzed vaccine effectiveness when two vaccine doses were given on-schedule (the second dose did not exceed 12 months) and off-schedule (the second dose exceeded 12 months as compared to when three doses were applied.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Of the 477 hospitalized patients during 2018\u20132020, the vaccine history was known for 421 patients. 361 (85.8%) patients were not vaccinated, 12 (2.8%) had received two doses only (on- and off- schedule), among them, 2 (0.5%) received two doses on-schedule, and 44 (10.4%) patients had received \u22653 doses. The calculated vaccination effectiveness was in the range from 94.6%\u201397.4% for both two doses only and three doses vaccination categories.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In Austria, the TBE vaccine based on strain Neud\u00f6rfl is by far the most used TBE vaccine, and thus the deduced conclusion of the authors was that this vaccine may be used in the USA according to its licensure using two doses for short-term protection of travelers to TBE endemic regions. For long-term protection, a third dose must be applied.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">(It is worthwhile to mention here that the Robert Koch-Institut [Berlin] is of the opinion that two doses of TBE vaccine given independent of the trademark confer 98% protection up to one year; see <a href=\"https:\/\/tbenews.com\/tbe\/snapshot-week-11-2022tbe-in-germany-yearly-report-by-the-rki\/\" data-type=\"URL\" data-id=\"https:\/\/tbenews.com\/tbe\/snapshot-week-11-2022tbe-in-germany-yearly-report-by-the-rki\/\">Snapshot week 11\/2022<\/a>).<\/p>\n<\/span>","protected":false},"excerpt":{"rendered":"<p>Pugh et al.Effectiveness of two doses of tick-borne encephalitis (TBE) vaccineJ. Travel Med. 2022; in press. doi:10.1093\/jtm\/taab193 Since autumn 2021, a TBE vaccine (based on the European subtype, strain Neud\u00f6rfl) has been licensed in the USA. The primary vaccination series consists of three injections for individuals aged \u22651 year. The doses are administered at day 0, 14 days to 3 months later (1\u20133 months for individuals aged 1\u201315 years) and 5\u201312 months after the second dose. Travelers mostly ask for health advice shortly before they travel, and thus there would not be sufficient time to complete the primary vaccination series prior to travelling to TBE endemic areas. Would two doses of TBE vaccine help to protect against TBE in the short term? This has been answered by a recently published analysis of TBE vaccination in Austria for the years 2018\u20132020. The authors analyzed vaccine effectiveness when two vaccine doses were given on-schedule (the second dose did not exceed 12 months) and off-schedule (the second dose exceeded 12 months as compared to when three doses were applied. Of the 477 hospitalized patients during 2018\u20132020, the vaccine history was known for 421 patients. 361 (85.8%) patients were not vaccinated, 12 (2.8%) had received two doses only (on- and off- schedule), among them, 2 (0.5%) received two doses on-schedule, and 44 (10.4%) patients had received \u22653 doses. The calculated vaccination effectiveness was in the range from 94.6%\u201397.4% for both two doses only and three doses vaccination categories. In Austria, the TBE vaccine based on strain Neud\u00f6rfl is by far the most used TBE vaccine, and thus the deduced conclusion of the authors was that this vaccine may be used in the USA according to its licensure using two doses for short-term protection of travelers to TBE endemic regions. For long-term protection, a third dose must be applied. (It is worthwhile to mention here that the Robert Koch-Institut [Berlin] is of the opinion that two doses of TBE vaccine given independent of the trademark confer 98% protection up to one year; see Snapshot week 11\/2022).<\/p>\n","protected":false},"author":1354,"featured_media":12864,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[18],"tags":[864,863,800,862],"coauthors":[81],"class_list":["post-18808","post","type-post","status-publish","format-standard","has-post-thumbnail","category-snapshot","tag-primary-vaccination-series","tag-travel","tag-usa","tag-vaccination-schedule"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Snapshot week 12\/2022Short-term protection of TBE vaccination for travelers - TBE Book<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Snapshot week 12\/2022Short-term protection of TBE vaccination for travelers - TBE Book\" \/>\n<meta property=\"og:description\" content=\"Pugh et al.Effectiveness of two doses of tick-borne encephalitis (TBE) vaccineJ. Travel Med. 2022; in press. doi:10.1093\/jtm\/taab193 Since autumn 2021, a TBE vaccine (based on the European subtype, strain Neud\u00f6rfl) has been licensed in the USA. The primary vaccination series consists of three injections for individuals aged \u22651 year. The doses are administered at day 0, 14 days to 3 months later (1\u20133 months for individuals aged 1\u201315 years) and 5\u201312 months after the second dose. Travelers mostly ask for health advice shortly before they travel, and thus there would not be sufficient time to complete the primary vaccination series prior to travelling to TBE endemic areas. Would two doses of TBE vaccine help to protect against TBE in the short term? This has been answered by a recently published analysis of TBE vaccination in Austria for the years 2018\u20132020. The authors analyzed vaccine effectiveness when two vaccine doses were given on-schedule (the second dose did not exceed 12 months) and off-schedule (the second dose exceeded 12 months as compared to when three doses were applied. Of the 477 hospitalized patients during 2018\u20132020, the vaccine history was known for 421 patients. 361 (85.8%) patients were not vaccinated, 12 (2.8%) had received two doses only (on- and off- schedule), among them, 2 (0.5%) received two doses on-schedule, and 44 (10.4%) patients had received \u22653 doses. The calculated vaccination effectiveness was in the range from 94.6%\u201397.4% for both two doses only and three doses vaccination categories. In Austria, the TBE vaccine based on strain Neud\u00f6rfl is by far the most used TBE vaccine, and thus the deduced conclusion of the authors was that this vaccine may be used in the USA according to its licensure using two doses for short-term protection of travelers to TBE endemic regions. For long-term protection, a third dose must be applied. (It is worthwhile to mention here that the Robert Koch-Institut [Berlin] is of the opinion that two doses of TBE vaccine given independent of the trademark confer 98% protection up to one year; see Snapshot week 11\/2022).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/\" \/>\n<meta property=\"og:site_name\" content=\"TBE Book\" \/>\n<meta property=\"article:published_time\" content=\"2022-03-21T06:03:39+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-03-22T07:39:55+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1180\" \/>\n\t<meta property=\"og:image:height\" content=\"250\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Michael Br\u00f6ker\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Michael Br\u00f6ker\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\\\/\"},\"author\":{\"name\":\"Shaqeez\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#\\\/schema\\\/person\\\/2bc2ab1f56f93257537a0ce8de903224\"},\"headline\":\"Snapshot week 12\\\/2022 Short-term protection of TBE vaccination for travelers\",\"datePublished\":\"2022-03-21T06:03:39+00:00\",\"dateModified\":\"2022-03-22T07:39:55+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\\\/\"},\"wordCount\":329,\"publisher\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/TBE-Snapshots.jpg\",\"keywords\":[\"primary vaccination series\",\"travel\",\"USA\",\"vaccination schedule\"],\"articleSection\":[\"Snapshot\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\\\/\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\\\/\",\"name\":\"Snapshot week 12\\\/2022 Short-term protection of TBE vaccination for travelers - 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TBE Book","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/","og_locale":"en_US","og_type":"article","og_title":"Snapshot week 12\/2022Short-term protection of TBE vaccination for travelers - TBE Book","og_description":"Pugh et al.Effectiveness of two doses of tick-borne encephalitis (TBE) vaccineJ. Travel Med. 2022; in press. doi:10.1093\/jtm\/taab193 Since autumn 2021, a TBE vaccine (based on the European subtype, strain Neud\u00f6rfl) has been licensed in the USA. The primary vaccination series consists of three injections for individuals aged \u22651 year. The doses are administered at day 0, 14 days to 3 months later (1\u20133 months for individuals aged 1\u201315 years) and 5\u201312 months after the second dose. Travelers mostly ask for health advice shortly before they travel, and thus there would not be sufficient time to complete the primary vaccination series prior to travelling to TBE endemic areas. Would two doses of TBE vaccine help to protect against TBE in the short term? This has been answered by a recently published analysis of TBE vaccination in Austria for the years 2018\u20132020. The authors analyzed vaccine effectiveness when two vaccine doses were given on-schedule (the second dose did not exceed 12 months) and off-schedule (the second dose exceeded 12 months as compared to when three doses were applied. Of the 477 hospitalized patients during 2018\u20132020, the vaccine history was known for 421 patients. 361 (85.8%) patients were not vaccinated, 12 (2.8%) had received two doses only (on- and off- schedule), among them, 2 (0.5%) received two doses on-schedule, and 44 (10.4%) patients had received \u22653 doses. The calculated vaccination effectiveness was in the range from 94.6%\u201397.4% for both two doses only and three doses vaccination categories. In Austria, the TBE vaccine based on strain Neud\u00f6rfl is by far the most used TBE vaccine, and thus the deduced conclusion of the authors was that this vaccine may be used in the USA according to its licensure using two doses for short-term protection of travelers to TBE endemic regions. For long-term protection, a third dose must be applied. (It is worthwhile to mention here that the Robert Koch-Institut [Berlin] is of the opinion that two doses of TBE vaccine given independent of the trademark confer 98% protection up to one year; see Snapshot week 11\/2022).","og_url":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/","og_site_name":"TBE Book","article_published_time":"2022-03-21T06:03:39+00:00","article_modified_time":"2022-03-22T07:39:55+00:00","og_image":[{"width":1180,"height":250,"url":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg","type":"image\/jpeg"}],"author":"Michael Br\u00f6ker","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Michael Br\u00f6ker","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/#article","isPartOf":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/"},"author":{"name":"Shaqeez","@id":"https:\/\/tbenews.com\/tbe\/#\/schema\/person\/2bc2ab1f56f93257537a0ce8de903224"},"headline":"Snapshot week 12\/2022 Short-term protection of TBE vaccination for travelers","datePublished":"2022-03-21T06:03:39+00:00","dateModified":"2022-03-22T07:39:55+00:00","mainEntityOfPage":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/"},"wordCount":329,"publisher":{"@id":"https:\/\/tbenews.com\/tbe\/#organization"},"image":{"@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/#primaryimage"},"thumbnailUrl":"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg","keywords":["primary vaccination series","travel","USA","vaccination schedule"],"articleSection":["Snapshot"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/","url":"https:\/\/tbenews.com\/tbe\/snapshot-week-12-2022short-term-protection-of-tbe-vaccination-for-travelers\/","name":"Snapshot week 12\/2022 Short-term protection of TBE vaccination for travelers - 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