{"id":27905,"date":"2026-03-03T12:21:08","date_gmt":"2026-03-03T04:21:08","guid":{"rendered":"https:\/\/tbenews.com\/tbe\/?p=27905"},"modified":"2026-03-03T12:22:43","modified_gmt":"2026-03-03T04:22:43","slug":"snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection","status":"publish","type":"post","link":"https:\/\/tbenews.com\/tbe\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\/","title":{"rendered":"Snapshot week 11\/2026<br> Myocarditis associated with TBE virus infection"},"content":{"rendered":"<span class=\"cb-itemprop\" itemprop=\"reviewBody\">\n<p class=\"wp-block-paragraph\">Seneghini et al. <br>Extraneurological presentations of tick-borne encephalitis virus: A rare case of TBEV-associated myocarditis with fever and bicytopenia and a systematic literature review. <em>Case Rep Infect Dis.<\/em> 2026;2026:3051689. doi:10.1155\/2026\/3051689.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Infection with tick-borne encephalitis (TBE) virus typically follows a biphasic course, characterized by fever and headache during the initial phase and central nervous system involvement in the second phase. Extraneurological manifestations such as hepatitis, myositis, and thrombocytopenia are uncommon.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A case of myocarditis was reported in a 77-year-old patient from eastern Switzerland who had not received TBE vaccination. The patient presented to the emergency department with acute chest pain three weeks after a tick bite. Laboratory findings revealed moderate neutropenia and thrombocytopenia. Cardiac biomarkers and hepatic enzymes were mildly elevated. The initial electrocardiogram demonstrated mild sinus bradycardia. Blood cultures were negative for bacterial growth, and extensive viral testing yielded negative results.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Early TBE virus infection was suspected. Serological testing showed positive IgM antibodies, followed by seroconversion to high IgG titers, supporting recent infection. The authors concluded that there was a strong causal association between acute myocarditis and TBE virus infection in this case.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A review of the literature indicated that myocarditis has also been reported in association with other flavivirus infections. Although extraneurological manifestations of TBE virus infection remain rare, awareness of these atypical presentations is important to prevent complications and ensure appropriate patient management.<\/p>\n<\/span>","protected":false},"excerpt":{"rendered":"<p>Seneghini et al. Extraneurological presentations of tick-borne encephalitis virus: A rare case of TBEV-associated myocarditis with fever and bicytopenia and a systematic literature review. Case Rep Infect Dis. 2026;2026:3051689. doi:10.1155\/2026\/3051689. Infection with tick-borne encephalitis (TBE) virus typically follows a biphasic course, characterized by fever and headache during the initial phase and central nervous system involvement in the second phase. Extraneurological manifestations such as hepatitis, myositis, and thrombocytopenia are uncommon. A case of myocarditis was reported in a 77-year-old patient from eastern Switzerland who had not received TBE vaccination. The patient presented to the emergency department with acute chest pain three weeks after a tick bite. Laboratory findings revealed moderate neutropenia and thrombocytopenia. Cardiac biomarkers and hepatic enzymes were mildly elevated. The initial electrocardiogram demonstrated mild sinus bradycardia. Blood cultures were negative for bacterial growth, and extensive viral testing yielded negative results. Early TBE virus infection was suspected. Serological testing showed positive IgM antibodies, followed by seroconversion to high IgG titers, supporting recent infection. The authors concluded that there was a strong causal association between acute myocarditis and TBE virus infection in this case. A review of the literature indicated that myocarditis has also been reported in association with other flavivirus infections. Although extraneurological manifestations of TBE virus infection remain rare, awareness of these atypical presentations is important to prevent complications and ensure appropriate patient management.<\/p>\n","protected":false},"author":94681,"featured_media":12864,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[18,1324],"tags":[1344,1345,228],"coauthors":[1108],"class_list":["post-27905","post","type-post","status-publish","format-standard","has-post-thumbnail","category-snapshot","category-snapshot-2026","tag-extraneuronal-symptoms","tag-myocarditis","tag-switzerland"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Snapshot week 11\/2026 Myocarditis associated with TBE virus infection - TBE Book<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tbenews.com\/tbe\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Snapshot week 11\/2026 Myocarditis associated with TBE virus infection - TBE Book\" \/>\n<meta property=\"og:description\" content=\"Seneghini et al. Extraneurological presentations of tick-borne encephalitis virus: A rare case of TBEV-associated myocarditis with fever and bicytopenia and a systematic literature review. Case Rep Infect Dis. 2026;2026:3051689. doi:10.1155\/2026\/3051689. Infection with tick-borne encephalitis (TBE) virus typically follows a biphasic course, characterized by fever and headache during the initial phase and central nervous system involvement in the second phase. Extraneurological manifestations such as hepatitis, myositis, and thrombocytopenia are uncommon. A case of myocarditis was reported in a 77-year-old patient from eastern Switzerland who had not received TBE vaccination. The patient presented to the emergency department with acute chest pain three weeks after a tick bite. Laboratory findings revealed moderate neutropenia and thrombocytopenia. Cardiac biomarkers and hepatic enzymes were mildly elevated. The initial electrocardiogram demonstrated mild sinus bradycardia. Blood cultures were negative for bacterial growth, and extensive viral testing yielded negative results. Early TBE virus infection was suspected. Serological testing showed positive IgM antibodies, followed by seroconversion to high IgG titers, supporting recent infection. The authors concluded that there was a strong causal association between acute myocarditis and TBE virus infection in this case. A review of the literature indicated that myocarditis has also been reported in association with other flavivirus infections. Although extraneurological manifestations of TBE virus infection remain rare, awareness of these atypical presentations is important to prevent complications and ensure appropriate patient management.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/tbenews.com\/tbe\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\/\" \/>\n<meta property=\"og:site_name\" content=\"TBE Book\" \/>\n<meta property=\"article:published_time\" content=\"2026-03-03T04:21:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-03T04:22:43+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/tbenews.com\/tbe\/wp-content\/uploads\/2017\/11\/TBE-Snapshots.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1180\" \/>\n\t<meta property=\"og:image:height\" content=\"250\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"logesan\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"logesan\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\\\/\"},\"author\":{\"name\":\"logesan\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#\\\/schema\\\/person\\\/eea00490409f8d848a28485d0f68fac3\"},\"headline\":\"Snapshot week 11\\\/2026 Myocarditis associated with TBE virus infection\",\"datePublished\":\"2026-03-03T04:21:08+00:00\",\"dateModified\":\"2026-03-03T04:22:43+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\\\/\"},\"wordCount\":232,\"publisher\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/TBE-Snapshots.jpg\",\"keywords\":[\"Extraneuronal symptoms\",\"myocarditis\",\"Switzerland\"],\"articleSection\":[\"Snapshot\",\"Snapshot 2026\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\\\/\",\"url\":\"https:\\\/\\\/tbenews.com\\\/tbe\\\/snapshot-week-11-2026-myocarditis-associated-with-tbe-virus-infection\\\/\",\"name\":\"Snapshot week 11\\\/2026 Myocarditis associated with TBE virus infection - 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Extraneurological presentations of tick-borne encephalitis virus: A rare case of TBEV-associated myocarditis with fever and bicytopenia and a systematic literature review. Case Rep Infect Dis. 2026;2026:3051689. doi:10.1155\/2026\/3051689. Infection with tick-borne encephalitis (TBE) virus typically follows a biphasic course, characterized by fever and headache during the initial phase and central nervous system involvement in the second phase. Extraneurological manifestations such as hepatitis, myositis, and thrombocytopenia are uncommon. A case of myocarditis was reported in a 77-year-old patient from eastern Switzerland who had not received TBE vaccination. The patient presented to the emergency department with acute chest pain three weeks after a tick bite. Laboratory findings revealed moderate neutropenia and thrombocytopenia. Cardiac biomarkers and hepatic enzymes were mildly elevated. The initial electrocardiogram demonstrated mild sinus bradycardia. Blood cultures were negative for bacterial growth, and extensive viral testing yielded negative results. Early TBE virus infection was suspected. Serological testing showed positive IgM antibodies, followed by seroconversion to high IgG titers, supporting recent infection. The authors concluded that there was a strong causal association between acute myocarditis and TBE virus infection in this case. A review of the literature indicated that myocarditis has also been reported in association with other flavivirus infections. 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