Page 258 - TBE_Book_V2_2019

Chapter 12b: TBE in China

Table 1: Virus, vector, transmission of TBE in China
Viral subtypes,
Far Eastern TBEV subtype (TBEV-FE)
distribution
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Reservoir animals Mice and insectivorous animals; migratory birds; lagomorphs, goats
I. persulcatus; however, TBEV has also been isolated from
Infected tick species (%) Haemaphysalis concinna, Haemaphysalis japonica, Dermacentor
5
silvarum, and Ixodes ovatus
Infection rate among the 13.0–14.3%, 0.79–6.45%, and 0–37.5% in northeastern China;
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ticks 14.3–47.7% in northwestern China; 8.3% in southwestern China
Dairy product
Not known
transmission
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6
Serological infection rate 19.7% in southwestern China, 35.4% in northwestern China,
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8
10
in healthy people 0–10.9%, 0–9.8%, 7.6% in northeastern China
Table 2: TBE reporting and vaccine prevention in China
Mandatory TBE reporting Heilongjiang Province only

Other TBE Surveillance No

Biphasic disease not reported in China.
Different symptoms among patients with different disease severities
In the early 1950s, case fatality rate (CFR) of TBE in the northeastern
forest areas was over 25%, but since the 1980s it has decreased to
Special clinical features 1,2,11
around 8%. Long-lasting sequelae of TBE are common, almost one-
third of the patients in the 1952 outbreak had paralysis in the neck
2
muscles or the shoulder muscles. Recently the complications of TBE
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over a 10-year period reported to be 16.6% (90/542).
TaiSenBao produced in China with Sen-Zhang strain as seed strain in
Available vaccines
primary hamster kidney (PHK) cells
Vaccination
recommendations and No
reimbursement
Vaccine uptake by age
group/risk group/general No information available, estimated to be low
population
CFR 25% in 1950s, and decreased to <10% after 1980s 1,2,11

Name, address/website
Chinese Center for Disease Prevention and Control:
of TBE National Reference http://ivdc.chinacdc.cn/
Center

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