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Chapter 12b: TBE in Czech Republic


          Table 1: Virus, vector, transmission of TBE in the Czech Republic
          Viral subtypes, distribution  European subtype - no other information available
                                  Apodemus sylvaticus, Apodemus flavicollis, Myodes glareolus,
          Reservoir animals       Microtus agrestis, Sciurus vulgaris, Erinaceus roumanicus,
                                                           10
                                  Sorex araneus, Talpa europaea
                                  Capreolus capreolus, Cervus elaphus, Sus scrofa, Canis lupus,
          Indicator animals                                                 10
                                  Oeservis ammon, Bos taurus, Capra aegagrus hircus
                                                              11
          Infected tick species (%)   1970–2017: 156/123,098 (0.127%)
                                                              6,9
                                  Rare: 1997-2008: 0.9%; 2017: 0.6%
          Dairy product transmission                                  8
                                  Children and adolescents (1993-2007): 5.4%


          Table 2: TBE reporting and vaccine prevention in the Czech Republic

                                  Each case of TBE is reported by the diagnosing physicians to the
                                  respective public health authorities after obtaining positive findings
          Mandatory TBE reporting
                                  from biological specimens. Only confirmed cases on the basis of
                                                               1
                                  clinical and lab criteria are reported.
          Other TBE surveillance   No information available
                                                              10
                                  Bi-phasic disease: 1994-1997: 80%
                                                                     5
                                  Children and adolescents (1993-2012): 58%
                                  Risk groups: No information available

                                                                                  5
          Special clinical features   % with sequelae: children and adolescents (1993-2012): 3%

                                                                        6,9
                                  Mortality: case fatality rate (1970-2008):0.55%
                                             8
                                  (2017): 0.73%
                                             8
                                  (2018): 0.56%
                                                                      8
                                  Children and adolescents (1960-2007): 0.2%
                                  FSME-IMMUN (Baxter, Pfizer) since 1990,
          Available vaccines      Encepur (Novartis, GSK) since 1996.
                                  Doses sold: No information available
          Vaccination             First recommendation 1990, last recommendation Feb. 8, 2016.
          recommendations and     Partial reimbursement from health insurances started in 1993,
          reimbursement           different strategies of different health insurances in individual years.

          Vaccine uptake by age   No valid nationwide information available, results from telephone
          group/risk group/general   surveys in 2009, 2013, and 2015 indicate a vaccine uptake in the
          population              general population of 16, 23, 24% 2,3,4
          Name, address/website of  National Reference Laboratory for arboviruses, Public Health Institute
          TBE National Reference   of Ostrava, Partyzánské nám. 7, 702 00 Ostrava
                                                                          11
          Center                  https://www.zuova.cz/Home/Page/NRL-arboviry


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