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Chapter 9: Immunology of TBEV infection
Upon a tick bite, TBEV is transmitted into the skin where it infects local cells including fibroblasts and antigen presenting cells. This creates an inflammatory environment at the bite site leading to immune cell infiltration. Infected antigen presenting cells are believed to migrate to the draining lymph nodes and cont
Figure 1: TBE disease progression from TBEV-infected tick bite to the development of the second
(meningoencephalitic) phase of TBE.
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162 were adapted from Servier Medical Art (http://smart.servier.com/).
