Page 298 - TBE_Book_V2_2019

Chapter 12b: TBE in Germany

Overview of TBE in Germany

Table 1: Virus, vector, transmission of TBE in Germany

Viral subtypes, distribution European TBEV subtype 7,8,13,14

Main vertebrate reservoir animals assumed – Myodes glareolus,
Apodemus flavicollis, Apodemus agrarius, Apodemus sylvaticus,
Reservoir animals
Microtus agrestis and Microtus arvalis, and Myodes glareolus;
10
detailed information and studies missing.
I. ricinus (0.1–5%);
Infected tick species (%) D. reticulatus (0,5%)
(Chitimia-Dobler et al. submitted; Dobler, personal communication.)
2016 first outbreak by goat milk and goat cheese for > 50 years in
Germany; 2 patients;
14
Dairy product transmission 2017 outbreak in school with 8 patients
(Dobler, personal communication)

Table 2: TBE reporting and vaccine prevention in Germany
All patients with confirmed TBE by serological methods (TBEV IgM ±
IgG) or by virus detection are reported to the State Public Health
Mandatory TBE reporting
Authorities and to the Federal State Public Health Authority
(Robert Koch-Institute: https://www.rki.de)

Other TBE surveillance n/a

Biphasic disease in about 50%
Special clinical features Risk groups: permanent inhabitants and visitors of highly endemic
9
areas; mainly acquired during leisure activities
40% of patients meningoencephalitis, 10%
meningoencephalomyelitis; No reliable data available on

neurological sequelae; in a large study 40–50% of patients with
9
long-term sequelae; mortality rate 1–2%
Encepur Erwachsene, Encepur Kinder,
Available vaccines
FSME-IMMUN Erwachsene, FSME-IMMUN Kinder
Vaccination
All inhabitants and visitors of known endemic areas with a risk of
recommendations and tick contact; [STIKO recommendation (https://www.rki.de)]
reimbursement
Vaccine uptake by age group Vaccination rates in endemic areas 15 to 50%, depending on the
/ risk group/ general district
population (Survey of the German Society of Consumption Research)
Name, address/website of Robert Koch-Institute (Federal Authority of Public Health),
TBE National Reference Nordufer 20, 13353 Berlin, Germany (https://www.rki.de)
Center

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