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Chapter 12b: TBE in Latvia
Table 2: TBE reporting and vaccine prevention in Latvia
Mandatory notification since 1955.
Based on national legislation, there is countrywide mandatory case-based
passive reporting and the European Centre for Disease Prevention and
Control (ECDC) case definition for TBE was adapted in Cabinet Regulations
Mandatory TBE in 2012. Aggregated data on TBE cases are available from 1955 and case-
reporting 3,20 based data in electronic format are available from 2007.
Prior to 2012, the case definition of TBE in Latvia included (1) hospitalization
because of central nervous system disease and (2) confirmation of infection
with TBE virus by laboratory diagnosis, usually by the demonstration of
specific IgM antibodies by ELISA.
Other TBE surveillance Not applicable
Study done in Children Clinical university hospital reveals that Biphasic fever
course was presented in 50% (n=41) in children treated in the hospital at
9
the time period 2000-2015.
Special clinical
features Annual mortality varies from 0 to 1.3% (1973-2009) and is not related to the
overall incidence of TBE. Follow-up for 1-13 years of a cohort of 100
patients revealed long-term sequelae in over 50%, more commonly in those
3
suffering focal forms of acute TBE.
TicoVac (0.25 and 0.5 ml) since 1995 (FSME Immun)
Encepur adults since 2001
Available vaccines 2,21 - Delivery interruption - 12.2012. till 03.2014., therefore sold less doses
Encepur Children since 2002
- Delivery interruption 04.2013 to 09.2014, therefore sold less doses
There is only a partial National Immunization Program in place which
recommends vaccination for children and adolescents living in endemic
areas since 2007 and has provided vaccine free of charge for children living
Vaccination in highly endemic areas since 2006 and orphans / children without parental
recommendations and care in the whole country since 2010. Vaccination is mandatory for high risk
reimbursement 15,16,22 groups and /or those with high occupational exposure such as forest
workers, military personnel, and lab workers and is paid by the employer.
Vaccination is also recommended, but not reimbursed for adults.
Also most insurance companies covers TBE vaccination costs.
The vaccination uptake overall is 53% in 2015.
Vaccine uptake by age In Latvia, approximately 22% of children had been vaccinated by the end of
group/risk group/ 2010, most (77%) of whom were living in highly endemic areas, the cost of
general population 15,17 which is reimbursed by the state. The vaccination rate for the national
population was 39% in 2009 and 41% in 2010.
Center of Disease Prevention and Control of Latvia
https://www.spkc.gov.lv
Name, address/ Duntes iela 22, k-5, Rīga, Latvija, LV 1005
website of TBE NRC Diagnostics: Latvian Centre of Infectious Diseases
(Latvijas Infektoloģijas centrs) of the Riga East University Hospital:
https://www.aslimnica.lv/en/saturs/latvian-centre-infectious-diseases
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