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Chapter 12b: TBE in Russia

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group. In 1950-1960 second generation of awareness and absence of an NIP – regions
TBE vaccine based on chicken embryotic cell are purchasing vaccine doses on their own
culture for virus reproduction was establish- according to the availability of a local budget
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ed . The vaccine was “upgraded” in 1961- (Figure 3). 16,23,24
1966, tested in Western Siberia with good
field effectiveness. In the 1980s further im- Nonspecific prevention is possible for all tick-
provement in reactogenicity were achieved by borne infections. Acaricidal treatment of
a purified, lyophilized third generation vaccine endemic territories with special chemicals like
and this is currently licensed and used in cipermetrin 25% or analogues is regarded to
Russia. 21,22 be the main measure nowadays. Compared
with 2011, these measures more than doubled
In 2017 in Russia primary and booster series of and in 2016 over 17,600,000 m2 of the most
TBE vaccines were administered to 3.1 million populated and actively used areas (i.e. parks,
persons. In the last 6 years, the planned camps and recreation zones, hospital, hotels,
annual immunization rates have not exceeded school and kindergarten territories) were
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3.3 million persons per year, which is about 4 treated this way in the RF.
times lower than required due to insufficient

Overview of TBE in Russia

Table 1: Virus, vector, transmission of TBE in Russia

Viral subtypes, distribution European, Siberian, and Far Eastern TBEV subtypes

Reservoir animals Vertebrate reservoir animals assumed
6.3% infected tick from people after tick bite
Infected tick species (%)
5.7% infected tick from natural foci
Dairy product transmission Rare

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