Page 414 - TBE_Book_V2_2019

Chapter 12b: TBE in South Korea

Table 2: TBE reporting and vaccine prevention in South Korea

Yes: TBE is a group 4 Nationally Notifiable Infectious Disease in South
7
Korea

Case definition: laboratory-confirmed patient

1. Clinical criteria: person with symptoms of inflammation of the central
nervous system, including meningitis, meningoencephalitis,
Mandatory TBE encephalomyelitis, etc.

reporting 2. Laboratory criteria
 Detection of TBE-specific IgM antibody in the serum/CSF
(confirmation of TBE-specific antibodies is required by serum
neutralization assay)
 Seroconversion or ≥4-fold increase of TBE-specific antibodies in
paired serum samples
 Detection of TBE viral nucleic acid in clinical specimen

Other TBE surveillance None

Special clinical features No information available

Available vaccines Not available

Contact: infection@korea.ac.kr 4. Yun SM, Song BG, Choi W, et al. Prevalence of
tick-borne encephalitis virus in ixodid ticks
Citation: collected from the republic of Korea during 2011
-2012. Osong Public Health Res Perspect.
Song JY. TBE in South Korea. Chapter 12b. In:
2012;3:213-21.
Dobler G, Erber W, Bröker M, Schmitt HJ, eds.
The TBE Book. 2nd ed. Singapore: Global 5. Yun SM, Lee YJ, Choi W, et al. Molecular
Health Press; 2019. doi: 10.33442/978-981-14- detection of severe fever with thrombo-
0914-1_12b-31 cytopenia syndrome and tick-borne encephalitis
viruses in ixodid ticks collected from vegetation,

Republic of Korea, 2014. Ticks Tick Borne Dis.
2016;7:970-8.
References
6. Ree HI. In: Medical Entomology: Medical
1. Kim SY, Jeong YE, Yun SM, Lee IY, Han MG, Ju YR.
Arthropodology. 4th ed. Seoul: Komoonsa;
Molecular evidence for tick-borne encephalitis
2005:345-90.
virus in ticks in South Korea. Med Vet Entomol.
2009;23:15-20. 7. Yoo SJ, Park JH. Necessity of a Surveillance
System for Tick-borne Encephalitis. Osong Public
2. Kim SY, Yun SM, Han MG, et al. Isolation of tick-
Health Res Perspect. 2017;8:155
borne encephalitis viruses from wild rodents,
South Korea. Vector Borne Zoonotic Dis. 8. Korean Centers for Disease Control and
2008;8:7-13. Prevention. Case Definitions for National
Notifiable Infectious Diseases; 2016.
3. Ko S, Kang JG, Kim SY, et al. Prevalence of tick-
borne encephalitis virus in ticks from southern
Korea. J Vet Sci. 2010;11:197-203.

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