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Chapter 12b: TBE in Japan


           Table 1: Virus, vector, transmission of TBE in Japan

          Viral subtypes, distribution   Far-Eastern subtype

          Reservoir animals         Wild rodents 3,7,8
                                                  6
          Infected tick species (%)   I. ovatus (0.33%)
          Dairy product transmission   Not reported

           Table 2: TBE reporting and vaccine prevention in Japan
                                    Laboratory confirmed cases must be reported by physicians.

                                    Case definition: Isolation of TBEV or detection of TBEV genomic ribonucleic
          Mandatory TBE reporting   acid by RT-PCR from blood or cerebrospinal fluid; Detection of IgM
                                    antibodies against TBEV from blood or cerebrospinal fluid; detection of
                                    significant increase in neutralizing antibodies against TBEV in paired serum.
          Other TBE surveillance    No
          Special clinical features   Encephalitis and meningitis with typical neurological symptoms.
          Available vaccines        No
          Vaccination recommendations
                                    No
          and reimbursement
          Vaccine uptake by age group/risk   No
          group/general population
          Name, address/website of TBE
          NRC                       No


           Figure 1: TBEV-isolation and TBE cases in Japan 2-7
           The region of viral isolation and cases are indicated by orange color and hatching

























                                                                        TBE in Japan, K. Yoshii



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