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Chapter 8: TBE in animals

Outcome died all 5 dogs were euthanasied all 8 dogs died or were euthanized one fully recovered, one partially recovered 2 euthanized, 2 fully recovered 1 asymptomatic, 1 partially recovered, 3 fully recovered

Confirmation Antibody response Virus isolation IHC IHC, pathohistologic al changes Antibody response Antibody response (SNT in 2 dogs) Antibody response

Antibody response yes n.d. IgM in CSF in 2 dogs n.d. Yes (both dogs) yes yes

Antigen detection n.d. yes n.d. n.d. n.d. n.d. n.d.

Reference 81 82 20 25 83 18 10 CSF = cerebrospinal fluid; Ig = immunoglobulin; IHC = immunohistochemistry, n.d. = not determined; PCR = polymerase chain reaction; SNT = serum

Table 2: Case reports and case series of TBE in dogs
Clinical symptoms n.d. behavioral changes, fever, tremor, paresis, seizures ataxie, tetraparesis, fever, grand mal seizures tremor, ataxia, hyperesthesia, hem- tetraplegia, opisthotonus, anisocoria, miosis, nystagmus fever, hyperesthesia, seizures, opisthotonus, facial nerve paresis, strabismus ataxia, fever, weakness, tetraparesis, c

Dog breed 1 dog 1 Landseer 2 Rottweiler, 1 Greyhound, 1 Husky, 1 Golden Retriever 3 Husky, 1 Terrier-Mix, 1 Rottweiler, 1 Irish Setter, 1 Bastard, 1 Pekingese 1 Rottweiler, 1 Newfoundland dog 2 Rottweiler, 1 Newfoundland dog *, 1 Boxer 3 Rottweiler, 1 Fila Brasiliero, 1 Dachshound

Country Sweden Switzer- land Switzer- land Austria Germany Germany Czech Republic *1 dog was also published in a previous paper

Year 1960 1970 1993 1994 - 1997 1998 1996- 1998 2001 neutralization test

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