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Chapter 5: TBE in adults
Table 1: Overview of TBE long-sequelae in prospective and retrospective studies
Seroconversion without any obvious clinical Clinical presentations of the
signs is common and well documented, neurological (second) phase
especially in populations that are highly
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exposed to TBEV and ticks. In a study from The exact mechanism by which TBEV crosses
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Sweden, 25% of infected individuals the blood–brain barrier and invades the CNS
developed CNS disease. This proportion seems remains unclear. There are 4 proposed
to be lower with the TBEV-Sib and TBEV-FE mechanisms: I. Cytokine mediated (targeting
subtypes, where 70–95% of infections are the endothelium) whereby cytokines
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reported to remain without any symptoms.
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