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Chapter 2a: Virology

92. Silva PA, Pereira CF, Dalebout TJ, Spaan WJ, 101. Kopecký J, Grubhoffer L, Kovár V, Jindrák L,
Bredenbeek PJ. An RNA pseudoknot is Vokurková D. A putative host cell receptor for
required for production of yellow fever virus tick-borne encephalitis virus identified by anti-
subgenomic RNA by the host nuclease XRN1. J idiotypic antibodies and virus affinoblotting.
Virol. 2010;84:11395-406. Intervirology. 1999;42:9-16.

93. Muñoz-Jordan JL, Sánchez-Burgos GG, Laurent 102. Kroschewski H, Allison SL, Heinz FX, Mandl
-Rolle M, García-Sastre A. Inhibition of CW. Role of heparan sulfate for attachment
interferon signaling by dengue virus. Proc Natl and entry of tick-borne encephalitis virus.
Acad Sci U S A. 2003;100:14333-8. Virology. 2003;308:92-100.

94. Steffens S, Thiel HJ, Behrens SE. The RNA- 103. Mandl CW. Steps of the tick-borne
dependent RNA polymerases of different encephalitis virus replication cycle that affect
members of the family Flaviviridae exhibit neuropathogenesis. Virus Res. 2005;111:161-
similar properties in vitro. J Gen Virol. 74.
1999;80:2583- 90.
104. Miorin L, Romero-Brey I, Maiuri P, et al. Three
95. Černý J, Černá Bolfíková B, Valdés JJ, -dimensional architecture of tick-borne
Grubhoffer L, Růžek D. Evolution of tertiary encephalitis virus replication sites and
structure of viral RNA dependent trafficking of the replicated RNA. J Virol.
polymerases. PLoS One. 2014;9:e96070. 2013;87:6469- 81.

96. Cui T, Sugrue RJ, Xu Q, et al. Recombinant 105. Růzek D, Vancová M, Tesarová M, et al.
dengue virus type 1 NS3 protein exhibits Morphological changes in human neural cells
specific viral RNA binding and NTPase activity following tick-borne encephalitis virus
regulated by the NS5 protein. Virology. infection. J Gen Virol. 2009;90:1649-58.
1998;246:409 -17.
106. Palus M, Bílý T, Elsterová J, et al. Infection and
97. Eyer L, Šmídková M, Nencka R, et al. Structure injury of human astrocytes by tick-borne
-activity relationships of nucleoside analogues encephalitis virus. J Gen Virol. 2014;95:2411-
for inhibition of tick-borne encephalitis virus. 26.
Antiviral Res. 2016;133:119-29.
107. Bílý T, Palus M, Eyer L, et al. Electron
98. Eyer L, Valdés JJ, Gil VA, et al. Nucleoside tomography analysis of tick-borne encephalitis
inhibitors of tick-borne encephalitis virus. virus infection in human neurons. Sci Rep.
Antimicrob Agents Chemother. 2015;59:5483- 2015;5:10745.
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108. Offerdahl DK, Dorward DW, Hansen BT, Bloom
99. Best SM, Morris KL, Shannon JG, et al. ME. A three-dimensional comparison of tick-
Inhibition of interferon-stimulated JAK-STAT borne flavivirus infection in mammalian and
signaling by a tick-borne flavivirus and tick cell lines. PLoS One. 2012;7:e47912.
identification of NS5 as an interferon
antagonist. J Virol. 2005;79:12828-39. 109. Mlera L, Offerdahl DK, Martens C, et al.
Development of a model system for tick-borne
100. Werme K, Wigerius M, Johansson M. Tick- flavivirus persistence in HEK 293T cells. MBio.
borne encephalitis virus NS5 associates with 2015;6:e00614.
membrane protein scribble and impairs
interferon-stimulated JAK-STAT signalling. Cell 110. Prikhod’ko GG, Prikhod’ko EA, Pletnev AG,
Microbiol. 2008;10:696-712. Cohen JI. Langat flavivirus protease NS3 binds
caspase-8 and induces apoptosis. J Virol.
2002;76:5701-10.

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